Anti-HEV IgM and IgG can be divided into two kinds of antibodies, Anti-HEV IgM and recent infection, infection in the early liver E (around the beginning of the acute phase) appears to last about five months and then disappears. Anti-HEV IgG appeared later than IgM, may be present in the body at least 5 years of infection indicators for ever. But many studies have shown, E liver antibody (either IgM or IgG) is not a good indicator of infection, since confirmed by PCR in patients with acute liver E, often undetectable Anti-HEV IgM or IgG, expressed antibody sensitivity is poor. Therefore, only the reference antibody measurement results can not be used as a basis for diagnosis.
E liver virus and hepatitis A infection pathway similar to fecal-oral infection based. E liver infection mostly sporadic cases of outbreak (outbreaks) occur rarely. Study found that regional epidemic E liver and contaminated water mostly related to improvement in water control, the new cases disappear. E liver incubation period of about 2 to 10 weeks, the majority of patients with flu-like symptoms appear, a few evolve into acute hepatitis, but it will not develop into chronic hepatitis or cirrhosis.
E and A liver infection liver age is slightly different, A liver infection in childhood when, and E in the liver and more infected between the ages of 15-40. Hepatitis E cases, cases of acute deterioration of liver more than A, especially pregnant women infected with hepatitis E, its mortality rate can be as high as 20%.
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From:Elisa test kits
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