2,5-Di-tert-butylhydroquinone
Synonyms Dibutylhydroquinone; BHQ; 2,5-Ditertiary butyl hydroquinone; Antioxidant DTBHQ
Molecular Formula C14H22O2
Molecular Weight 222.33
CAS Registry Number 88-58-4
Melting point 215-220 ºC
Flash point 216 ºC
Physical Appearance: White solid
Solubility: Soluble in DMSO(25 mg/ml warm) and ethanol(25 mg/ml)
2,5-Di-tert-butylhydroquinone (DBHQ) has been shown to be a selective and potent inhibitor of endoplasmic reticulum Ca2+-ATPase which is shown to cause induction of Ca2+ release from agonist-insensitive and agonist-sensitive intracellular stores. In isolated rat hepatocyte studies, DBHQ was reported to induce a rapid increase in cytosolic Ca2+ concentration without loss of other microsomal enzyme activity, altering membrane permeability, or modification of microsomal protein thiols.
Storage
Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
tert-Butylhydroquinone (TBHQ, tertiary butylhydroquinone) is an aromatic organic compound which is a type of phenol. It is a derivative of hydroquinone, substituted with tert-butyl group.
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