Dengue Virus belongs to the Flaviviridae family of a flavivirus serotype subgroup , morphology and Japanese encephalitis virus similar, but smaller, about 17 ~ 25nm, divided by 1,2,3,4 four different antigenic serotypes in different strains of the same type have different antigen . Among the most widespread type 2 , among various types of viral antigen with cross , and Japanese encephalitis virus and West Nile virus as well as some the same antigen . Virus in Aedes albopictus mosquitoes and passaged cells (C6/36 cells ) , monkey kidney, hamster kidney primary and passaged cells can proliferate and produce significant cytopathic .
Dengue virus is spread mainly through Aedes aegypti (Aedes ae-gyPti) and Aedes albopictus (Aedesalbopictus) and other media insects , causing dengue (dengue fever, DF) as well as the high morbidity and mortality rates of dengue hemorrhagic fever (dengue hemorrhagic fever, DHF) and dengue shock syndrome (dengue shock syndrome, DSS). Patients and latent infection is the major source of infection of the disease , while the jungle primate is to maintain the virus circulating in nature animal host . The heating of the patient's blood brain inoculated into naive mice can be isolated fixed .
These diseases are widely prevalent in tropical and subtropical regions , is a widely distributed , the incidence of many infectious diseases harmful to humans . In Asia , the Pacific Islands and Central and South America and many other countries have caused a serious threat. After World War II , the Japanese have had a pop. In recent years, Asia, Africa and tropical South America and sub-tropical regions the incidence of dengue virus infection in a clear upward trend . China in 1978 in Foshan, Guangdong first discovered the disease , later in the Hainan and Guangxi and other places have been found .
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