Sunday, November 20, 2011

What is Sodium L-pyroglutamate

Sodium L-pyroglutamate is an uncommon amino acid derivative in which the free amino group of glutamic acid cyclizes to form a lactam. Molecular Formula:C5H6NNaO3. Molecular Weight:151.09.  It is found in many proteins including bacteriorhodopsin. N-terminal glutamine residues can spontaneously cyclize to become pyroglutamate. 
This is one of several forms of blocked N-terminals which present a problem for N-terminal sequencing using Edman chemistry, which requires a free primary amino group not present in pyroglutamic acid. CAS Number:28874-51-3 The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue.
Properties:
Density:  1.45
Melting point: 125°C
Packing: 25kg(net.) plastic drum or as the need of customer
More about: Sodium L-pyroglutamate Sale
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