Because ABP binds to T and DHT, these hormones are fabricated beneath lipophilic and become concentrated aural the luminal aqueous of the seminiferous tubules. The college levels of these hormones accredit spermatogenesis in the seminiferous tubules and agent maturation in the epididymis.
ABP has the aforementioned amino acerbic arrangement as sex hormone-binding globulin (SHBG); the aberration is the website of assembly and the accession of altered amoroso moieties. ABP contains 403 amino acids, consistent in a atomic weight of 44,533. Its gene is amid on chromosome 17.
ABP’s assembly is adapted beneath access of FSH on Sertoli cell, added by insulin, retinol, and testosterone.
ABP may aswell be buried in added organs; for instance, mice aftermath a salivary ABP.
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